In 2013, after the release of Bioshock Infinite, Irrational Games had a period of time with multiple layoffs—this was to facilitate a change in direction for the company. Recently, they have posted new job openings for an IT Manager and Senior Programmer. Details include Irrational Games wanting applicants to have knowledge of Unreal Engine 3 and 4, as well as having multiplayer experience.
Once the positions are filled, my bet is that there will be a new game in production. Any ideas as to what it might be?
Source: Irrational Games